astrocytes wiring the brain pdf

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The goal of this book has been to compile an overview of the most current findings on the diverse roles played by astrocytes in central nervous system (CNS) function and dysfunction, emphasizing how the connections that the astrocyte makes with other cells of the brain are essential for a variety of important neural functions. A key concept that we have highlighted throughout (wiring the brain) is that astrocytes are morphologically highly elaborated cells, establishing associations through their fine processes with practically all cellular types in the CNS. Such close morphological associations, together with the fact that astrocytes express a multitude of ion channels, transporters, and membrane receptors, endow these cells with the unique  capability to sense and influence diverse CNS functions.